LB936 Cutaneous T-cell lymphoma (CTCL) following B-cell lymphoma: A case series

Cutaneous T-cell lymphoma (CTCL) is associated with an increased risk of developing secondary malignancies, particularly lymphomas. However, the diagnosis prior to CTCL very rare. Herein we present cases two patients diagnosed a CTCL. The first patient was female in her late 50s history diffuse large B-cell (DLBL) breast status post chemo plus radiation who developed poikilodermatous scaly patches on arms and legs one year after DLBL diagnosis. Her condition initially managed as eczema refractory treatment until biopsy performed at outside clinic several years later revealed likely followed by confirmative biopsies demonstrating poikiloderma atrophicans vasculare. She treated acitretin 10 mg five times weekly narrowband UVB twice for 12 treatments, but self-discontinued both. recently initiated monthly extracorporeal photopheresis. second 70s melanoma presented outpatient dermatology evaluation erythematous macules groin pending breast. rash topical therapies demonstrated mycosis fungoides. preferred conservative therapy natural sunlight hydrocortisone, ultimately elected photopheresis disease progressed. response both yet be determined. These illustrate importance full workup erythematous, rashes especially setting other malignancy treatments conditions. Both had least unrevealing true underlying diagnosis, showing that multiple may necessary capture this